Analysis of the efficacy of lithium in the prevention of suicide in patients with mood disorders: an integrative review

Background: Mood disorders refer to those whose main symptom is a change in mood or affect, altering animosity and the way of feeling, thinking behaving. Since 1970s, number primary studies have pointed lithium's effectiveness reducing risk suicide. Objectives: To carry out an integrative review literature on efficacy lithium preventing suicide patients with disorders. Methodology: Integrative review, which used descriptors “lithium”, “prevention” “suicide” LILACS, SciELO PUBMED databases. Inclusion criteria were articles published English, randomized clinical trial type, between 2000 2022, indexed chosen databases available for full reading. The research was carried according PRISMA flowchart systematic reviews. Six selected review. Results Discussion: Three showed that did not reduce attempts bipolar affective disorder (BD) major depression. Differences doses, sociodemographic conditions, type control group may cause results be discrepant when compared each other. Conclusion: Although prevent suicidal behavior disorders, analyzed divergent regarding its this group.